COURSES
Biol202.006 Genetics and Molecular Biology
Structure and function of nucleic acids, DNA, and chromatin organization, principles of inheritance, phenotypic analysis, gene expression, gene regulation, and genetic engineering.
Biol202.S1 Science in Dublin, Ireland: Genetics and Molecular Biology
Biol202; a six week summer session course for UNC students held in Dublin, Ireland. Structure and function of nucleic acids, DNA, and chromatin organization, principles of inheritance, phenotypic analysis, gene expression, gene regulation, and genetic engineering. To be taken concurrently with an Irish Studies class.
Biol240 Cell Biology
The biological concepts and scientific competencies necessary for foundational mastery of cell biology.
Biol447/Biol447L Cell Biology Lecture and Lab
This is a CURE-based laboratory course offering students the chance to engage in cutting-edge molecular and cell biological research. The four-credit course (Biol447 & Biol447L co-requisite) is composed of lectures and laboratory research. Students will use the time to discuss the biological problem of study and relevant research publications, to learn techniques commonly used in biochemical research, to evaluate and discuss possible research approaches to investigate the biological problem of study, to perform biochemical and cell biological research to test hypotheses the students develop. Students will work with instructors to develop their work plans, including experimental design, performing the experimental work, analyzing the data, and present their data and conclusions. Students will work in small groups of three or four students. They will share data to produce reports and they can coordinate coming to the laboratory after instruction hours to complete experiments for themselves and other group members. The research will culminate in written reports and a final presentation.
Biol544L Diseases of the Cytoskeleton
This is a CURE-based laboratory course offering students the chance to engage in cutting-edge biochemical and cell biological research. The three-credit course is composed of lectures and laboratory research. Students will use the time to discuss the biological problem of study and relevant research publications, to learn techniques commonly used in biochemical research, to evaluate and discuss possible research approaches to investigate the biological problem of study, to perform biochemical and cell biological research to test hypotheses the students develop. Students will work with instructors to develop their work plans, including experimental design, performing the experimental work, analyzing the data, and present their data and conclusions. Students will work in small groups of two or three students. They will share data to produce reports and they can coordinate coming to the laboratory after instruction hours to complete experiments for themselves and other group members. The research will culminate in a final presentation.
Biol643 The Molecular Cytoskeleton
This seminar examines the molecular mechanisms of cytoskeletal components. The course surveys topics pertaining to the actin cytoskeleton and the microtubule cytoskeleton. Topics include 1) the core building blocks: actin and tubulin; 2) nucleators: Arp2/3 and gamma tubulin/gamma-TuRC/Augmin; 3) motors: myosin, kinesin and dynein; 4) regulators: formins and microtubule plus end binding proteins; 5) destabilizers: KinI and stathmin; and 6) kinetochore-microtubule attachments complexes. Primary literature is examined, presented, and critiqued. Each class examines topics through primary literature with a focus on molecular/mechanistic papers and complementary cell biology papers that correlate structure with mechanism. Emerging techniques in cell biology and structure will be discussed including single molecule techniques, optical trapping, single particle electron microscopy, x-ray crystallography, and small angle X-ray scattering. The course is intended to familiarize cell biologists with molecular mechanisms and protein structure, promoting proficiency in viewing, evaluating, and presenting structure models using molecular graphics programs in order to design and implement structure-based experiments. The seminar aims to develop presentation skills, scientific writing, as well as manuscript evaluation and critique.
Biol704 (Bioc704) Seminar in Biophysics
Analysis and presentation of primary literature in biophysics.
Biol705 (BBSP705) Course in Rigor and Reproducibility
A short course on Rigor and Reproducibility for graduate students, aligned with best practices and key topics central to NIH T32 training programs.
Bioc902 Biophysical Principles of Life
A summer course for underrepresented minorities. The course, taught by faculty members of the UNC Molecular and Cellular Biophysics Program, introduces students to the fundamentals of biophysics including the principles of thermodynamics, macromolecular structure, structural dynamics, kinetics, molecular forces, cellular forces, and the experimental techniques used to address these parameters. 2 Lectures (Protein Structure; Molecular Motors).
Biol395 Undergraduate Research
Students with extraordinary drive, enthusiasm, intellect, and reason are encouraged to explore opportunities for undergraduate research in the Slep laboratory. Permission of the instructor is required.
Biol495 Undergraduate Research - Honors
A continuation of an undergraduate research project initiated under Biol395, conducted in candidacy for Departmental Honors.
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GRADUATE PROGRAMS
Graduate students interested in joining the Slep lab can enter the lab via three programs: UNC Biology UNC Molecular and Cellular Biophysics Program UNC Curriculum in Genetics and Molecular Biology Prospective graduate students should apply via BBSP. |
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© Kevin Slep